2012年5月13日星期日
Patients with systemic lupus erythematosus pregnancy
Suffering from lupus erythematosus and lupus nephritis if the condition is well controlled and will not affect fertility. Children do not have a big impact. However, patients with lupus nephritis fertility must meet the following two conditions
A lupus activity stabilized
Judgment the seven indicators of lupus activity, including ① arthritis ② The the ANA-positive, decreased complement ③ rash, mucosal ulcers, hair loss, ④ pleurisy, pericarditis ⑤ epilepsy, lupus, headaches, mental disorders (6) vasculitis ⑦ urine changes, such as proteinuria and hematuria. Seven indicators, arthritis, pericarditis, vasculitis, myalgia, brain and kidney damage 3 are known as severe, if not the above performance become stable condition. Patients with lupus nephritis through active treatment, the condition is brought under control, like a normal work, study and life. As for pregnancy, you can consider the case of stable disease activity. Antiphospholipid antibodies and LN patients after pregnancy, abortion is closely related to, should be monitoring.
2, treatment of drug suspension for at least six months or more
Lupus nephritis patients taking hormone drugs and immunosuppressive agents to control the disease, these drugs can cause hormonal disorders in patients, resulting in the decline of women's ability to conceive, and hormone drugs can cause fetal malformations. Pregnancy itself also cause lupus patients with heart and kidney burden increase, induction of disease recurrence.
Patients with lupus nephritis when considering pregnancy, be sure to consider whether their condition is stable lupus nephritis, sustained clinical remission time is long enough, the use of small doses of hormones, immunosuppressants downtime for more than six months of pregnancy in such conditions For patients with lupus nephritis caused by the lowest kidney damage.
Lupus erythematosus have a certain genetic predisposition.
It was found that close relatives of lupus erythematosus incidence rate of 5-12% incidence of dizygotic twin who was 23-69%, indicating that genetic and disease related to the occurrence.
But in clinical practice, we have also seen many lupus patients are children born very healthy, and shall not lupus. For lupus is not hereditary, in fact, the causes of lupus erythematosus, including the result of a variety of integrated factors, including infections, endocrine, and environmental impact should be noted that the clinical findings that mental factors induce a very important cause and aggravate the disease.
Accordingly, only lupus erythematosus have a genetic predisposition, rather than a genetic disease, a clear lupus erythematosus there is no hereditary lupus patients need not worry too much about their own genetic disease would be to their own children.However, to do the best early pregnancy, genetic testing, there are clear of LN loci termination of pregnancy.
Finally: the patients with lupus nephritis should be noted that during the pregnancy
A close attention to the whole pregnancy process
Little attention during pregnancy may lead to disease progression, increased disease activity. In lupus patients during pregnancy be sure to pay close attention to changes in condition and some indicators of change. Deterioration in symptoms to seek medical treatment in a timely manner, follow the doctor's arrangements for the treatment of patients with lupus nephritis must not act arbitrarily.
2, pregnant patients with lupus nephritis should pay attention to proper diet and rest
Patients with lupus nephritis during pregnancy should pay more attention to diet and rest. Reasonable diet to reduce the recurrence rate of induced lupus nephritis, and also conditioning the body. Appropriate rest and avoid fatigue-induced lupus attack.
Summary: patients with lupus nephritis is not absolute, unable to bear children, but need only have a certain physical condition, must not ignore the condition and subjective to determine their own fertility problems, it is best to consult a professional nephrology doctor before making a decision, otherwise easy to produce a variety of pregnancy complications, and even a threat to the safety of patients as well as the life of the fetus.
订阅:
博文评论 (Atom)
没有评论:
发表评论