No clinical manifestations of renal biopsy in lupus nephritis how to infer the pathological type?

A definite link between the clinical manifestations and pathological changes in lupus nephritis. In general, the clinical manifestations of the normal glomerular and Department of membranous glomerulonephritis lighter, no urine abnormalities, can also be expressed as a latent nephritis; focal segmental proliferative glomerulonephritis type more than to hide nephritis, or chronic nephritis, a few can be manifested as nephrotic syndrome; diffuse proliferative nephritis was manifested as nephrotic syndrome (about 75%) and chronic nephritic syndrome; membranous lupus nephritis more performance for the nephrotic syndrome, but generally no significant hypertension, slow deterioration of renal function. At present, most scholars believe that the WHO histological type of limited value in the treatment and prognosis of lupus nephritis. However, in recent years, some scholars believe that the renal activity index and the chronic index important guiding treatment and prognosis. The activity index is defined by the representative of the activity of (potentially reversible) damage the ratings of those items, the sum of the percent of the total number of these projects include capillary proliferation, leukocyte infiltration, capillary wall destruction, nuclear condensation, cell crescent, platinum ear, transparent thrombosis, fibrin thrombus and cellulose deposition, interstitial cellular infiltration, acute tubular necrosis, vasculitis, according to the light of the various lesions, weight rated as 1, 2, 3 . The chronic Index is a total number of chronic sclerosing, atrophic and / or fibrosis score together, these projects include glomerular sclerosis, cellulose crescents and adhesions, interstitial sclerosis, tubular atrophy, arterial and arteriosclerosis, the light, re-rated as 1, 2, 3. Chronic index with advanced kidney disease was positively correlated. Activity in mild to moderately elevated prompt condition reversible after appropriate treatment, renal function improved or stable.Chronic index moderately elevated activity index moderately elevated, and still is a strong indication of the treatment. Severe activity index increased, the indication for active treatment, but it reflects the glomerular structure of severe, active destruction, can often lead to scar formation.