2012年4月13日星期五
Lupus nephritis, kidney damage manifested
About 70% of patients with varying degrees of renal damage in the clinical manifestations of varying degrees of proteinuria, microscopic hematuria is more common, often accompanied by tubular urine and renal function impairment. The majority of patients with renal impairment to a lesser degree. Some patients although the clinical symptoms, but are not the development of renal insufficiency. Only a small number of renal damage in patients with renal failure. Hypertension is often associated with renal failure extent, become an important factor affecting prognosis. (A) asymptomatic proteinuria and (or) the hematuria type: This type is more common.Mainly for light - moderate proteinuria (<2.5g or (and) hematuria. (B) type of acute nephritic syndrome: rare, clinical manifestations resembles a post-streptococcal acute nephritis. (C) rapidly progressive glomerulonephritis syndrome type: rare, clinically resembles rapidly progressive glomerulonephritis. Characterized by three months, serum creatinine increased by ≥ 1 times. Uremia occurred within weeks to months. (D) The nephrotic syndrome: This type is common, accounting for about 2/3, but not necessarily with hyperlipidemia. When not in treatment, the majority of 2 to 3 years to uremia. This type is often confused with primary nephrotic syndrome, it is noteworthy. (E) chronic nephritic syndrome: the performance of sustained proteinuria, hematuria, urinary tube, and varying degrees of edema, hypertension, anemia and renal insufficiency. Course of a long, delayed healing, and thus occurrence of uremia. (F) a small number of patients can be manifested as chronic tubule interstitial nephritis clinical manifestations of patients with clinical manifestations of the specific gravity and (or) reduce the osmotic pressure, nocturnal enuresis, high or hypokalemia and other electrolyte disorders. End-stage lupus nephritis uremia, the patient's clinical activities (including serology) may disappear or become typical.
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