Lupus nephritis kidney damage performance

Symptoms of lupus erythematosus kidney damage is almost a series of symptoms, including glomerular, tubulointerstitial, renal vascular disease, can also be abrupt onset can be insidious, the course is generally longer, with or without symptoms, can also be kidney damage as the only clinical manifestations. Edema is a common clinical manifestations tend to be the main reason for patients attending. The increase in nocturnal enuresis is one of the early symptoms often reflect the urinary concentration of dysfunction. About 1/6 patients with varying degrees of renal insufficiency at the time of diagnosis. According to its clinical manifestations can be divided into the following type:

    Asymptomatic proteinuria (1) or (and) the hematuria type: This type is more common, edema, hypertension, mild to moderate proteinuria (<2.5g / d) or (and) hematuria.

    (2) type of acute nephritic syndrome: rare, clinically resembles streptococcal infection, acute nephritis, acute onset of hematuria, proteinuria, urinary tube, may have edema, hypertension, and even acute renal decline.

    (3) rapidly progressive glomerulonephritis syndrome, type: rare, clinically resembles rapidly progressive glomerulonephritis, abrupt onset and rapid development of oliguria or anuria, hematuria, proteinuria, urinary tube, can be edema, often without high blood pressure or mild hypertension, rapidly deteriorating rapidly and the development of anemia and hypoproteinemia, renal function, uremia in the weeks and months.

    (4) nephrotic syndrome: This type is common, about 60% of patients with renal impairment performance for this type. The clinical manifestations of massive proteinuria (3.5g / d) and hypoproteinemia, severe edema, but not necessarily have high cholesterol.If not treated, the majority of 2 to 3 years, the development of uremia. This type is easy to be confused with primary nephrotic syndrome, it is noteworthy.

    (5) type of chronic nephritic syndrome: the performance of persistent proteinuria, hematuria, urinary tube, and varying degrees of edema, hypertension, anemia and renal insufficiency. Course of a long, delayed healing and poor prognosis.

    (6) The type of renal tubular syndrome: a rare renal tubular acidosis, nocturia, edema, hypertension, increased urine β2-microglobulin, half of the patients with renal dysfunction.

    (7) clinical "silence": the clinical symptoms and signs had no kidney involvement, performance, urine tests negative, but the pathological examination (particularly in the electron microscopy and immunofluorescence) positive.