Type, various types of features and treatment of lupus nephritis

1, Ⅰ type of lupus nephritis (lupus nephritis type 1, 2)
Renal tissue of lupus nephritis type Ⅰ, light microscope, normal structure, immunoglobulin and complement deposition in the use of immunofluorescence. The prognosis of this type of lupus nephritis does not require special treatment, but still need follow-up study, to prepare for any eventuality.
Two, lupus nephritis type Ⅱ (lupus nephritis type 2, 2)
Lupus nephritis type Ⅱ, this type of kidney damage in the glomerular mesangial area, which no mesangial cell proliferation is known as type Ⅱ A, the prognosis of such mild mesangial lesions without treatment; II B-type lesions mesangial seen the proliferation of mesangial cells and monocytes, accompanied by proteinuria 1g/24h and low complement C3 hyperlipidemia in the treatment of six weeks of treatment between -3 and generally use strong pine 20mg / d, after with the improvement in reduction of the disease remain. Lupus nephritis type Ⅱ, interstitial and vascular damage.
3, type Ⅲ and type Ⅳ of lupus nephritis (lupus nephritis type 3, 3 and 4, 4)
Ⅲ type of glomerular damage in lupus nephritis has been more significant, In addition to the mesangial focal stage glomerular capillary has been involved, but no more than 50% of the total glomerular Lupus nephritis type Ⅳ and Ⅲ type of the type of injury, the only damage the broader reach more than 50% of glomerular damage, and even more serious degree.
Pathological damage similar between the two treatment programs similar prognosis.The development of these two types of lupus nephritis in 10 years to up to 50% of ESRD, but also to strengthen the treatment to prolong the survival period of patients with both types of a very important point. Usually in the prognosis of treatment with glucocorticoids and cytotoxic drugs. The glucocorticoid prednisone-based, conventional dosage is to be carried out under the guidance of a doctor, and the need to maintain a specific time we must obey the doctor's orders. If necessary time to give methylprednisolone maintenance treatment, this effect is better, and minimal side effects. Cell poison drug is also commonly used treatment, glucocorticoid with the cell poison, drug combination more fully. But the cytotoxic onset interval is longer, often 3-4 months before onset.
4, lupus nephritis type Ⅴ
Ⅴ type of lupus nephritis is divided into four types, type Ⅴ, a comparison with idiopathic membranous nephropathy; type Ⅴ b diffuse mesangial changes; type Ⅴ c segmental proliferation or segmental sclerosis; V d-exist with diffuse proliferative glomerulonephritis of this type regardless of the clinical manifestations of organizational performance is similar to the type Ⅴ lupus nephritis.
This type of treatment of lupus nephritis to distinguish between what are membranous lupus nephritis or diffuse lupus nephritis, using different pathological drugs and treatment methods are very different, but also on the type of symptomatic treatment.
5, lupus nephritis type Ⅵ
Ⅵ type of lupus nephritis belong to the late lupus nephritis, but accounts for only 2% of all lupus nephritis type.